Proton beam therapy is an advanced form of external radiotherapy that uses high-energy proton beams instead of photon x-ray beams or electrons. Carefully measured doses of protons are delivered to the precise area needing treatment, using the latest IBA ProteusONE technology. This ensures that the delivery of proton beam therapy is highly accurate and prevents the risk of radiation reaching surrounding healthy tissue.
Radiotherapy is used to kill and destroy cancer cells. It utilises radiation in the form of high-energy x-rays, known as photons, to kill and damage the cancerous cells and prevent their growth and reproduction. It can be used as a non-surgical option to treat cancer, and it can also be used to shrink a tumour or in combination with other treatments.
The Rutherford Cancer Centres and Elekta are bringing the next generation of personalised adaptive radiotherapy technology to oncology centres across the UK, with the new MR-linac Elekta Unity now available at the Rutherford Cancer Centre North West in Liverpool.
Dr. Vijay Sharma is a consultant histopathologist and award-winning researcher with a clinical interest in breast pathology. His research interest is in the role of energy and energy metabolism in disease, with a specific interest in breast cancer and how energy metabolism interfaces with mechanisms of immune evasion.
He is also the pathology lead for the MBChB medical program in Liverpool, the Co-Lead for the LUB Biobank, the Digital Pathology lead for LCL and serves on several national breast cancer committees. He has also previously worked at BMJ Group, running an editorial team.
NCRI Breast group member
NCRI SPED group member
Learning, Teaching and Student Experience Award 2020-2021, University of Liverpool, The Virtual Anatomy and Pathology project - Winner.
Elected as a Fellow of the Royal Society of Biology - In recognition of significant contributions to Biology, 2018.
Wellcome Trust - Bursary, July 2016.
Fellow of the Royal College of Pathologists
Fellow of the Royal Society of Biology
Member of the Academy of Medical Educators
The Pathological Society of UK and Ireland, Member.
Association of Pulmonary Pathologists, Member
The British Pharmacology Society Faculty of Medical Leadership and Management, Founding Member
The Royal Statistical Society, Fellow.
British Medical Association, Member.
Association for Comprehensive Energy Psychology, Member.
Sharma V.*, The application of chaos theory and fractal mathematics to the study of cancer evolution: placing metabolism and immunity centre stage, Medical Research Archives, 4(6): no page numbers, 2016.
Sharma V., Rankin R., Fatal Kikuchi-like lymphadenitis associated with connective tissue disease: a report of two cases and review of the literature, SpringerPlus 4:167-176, 2015.
Sharma V., McNeill J.H., Epigenetic regulation of cardiac remodelling in the diabetic heart: the missing link in the gene-environment interaction, Journal of Research in the Pharmaceutical Sciences, 1:11-18, 2014.
Sharma V.*, Davey J.G.N., Humphreys C. and Johnston P.W., A new approach for measuring the quality and work of histopathology reporting, Histopathology 63: 130-136, 2013.
Sharma V.*, Proctor I., Winstanley A., Mortality in a busy teaching hospital during the junior doctor changeover: comparison with regional and national trends, British Journal of Hospital Medicine 74:167-169, 2013.
Sharma V., Minhas R., Explanatory models are needed to integrate RCT and observational data with the patient’s unique biology, Journal of the Royal Society of Medicine 105: 11-24, 2012.
Sharma V., McNeill J.H., Parallel effects of β-adrenoceptor blockade on cardiac function and fatty acid oxidation in the diabetic heart: confronting the maze, World Journal of Cardiology 3: 281-302, 2011
Sharma V., Sharma A., Saran V., Allard M.F. and McNeill J.H., β-receptor antagonist treatment prevents activation of cell death signalling in the diabetic heart independent of its metabolic actions. European Journal of Pharmacology 657:117-125, 2011.
Sharma V., Abraham T., So A., Allard M.F. and McNeill J.H., Functional effects of protein kinases and peroxynitrite on cardiac carnitine palmitoyltransferase-1 in isolated mitochondria, Molecular and Cellular Biochemistry 337: 223-237, 2010.
Sharma V.*, Deterministic chaos and fractal complexity in the dynamics of cardiovascular behaviour: perspectives on a new frontier, The Open Cardiovascular Medicine Journal 3: 110–123, 2009.
Sharma V. and McNeill J.H., To scale or not to scale: the principles of dose extrapolation, British Journal of Pharmacology 157(6):907-921, 2009.
Sharma V., Mustafa S., Patel N., Wambolt R., Allard M.F. and McNeill J.H. Stimulation of fatty acid oxidation by leptin is mediated by a nitric oxide-p38 MAPK-dependent mechanism, European Journal of Pharmacology 617: 113-117, 2009.
Sharma V., Dhillon P., Parsons H., Allard M.F. and McNeill J.H., Metoprolol represses PGC-1alpha-mediated carnitine palmitoyltransferase-1 expression in the diabetic heart, European Journal of Pharmacology 607: 156-166, 2009.
Sharma V., Parsons H., Allard M.F. and McNeill J.H., Metoprolol increases the expression of 3-adrenoceptors in the diabetic heart: Effects on nitric oxide signaling and forkhead transcription factor-3, European Journal of Pharmacology 595: 44-51, 2008.
Sharma V., Dhillon P., Wambolt R., Parsons H., Brownsey R., Allard M.F. and McNeill J.H., Metoprolol improves cardiac function and modulates cardiac metabolism in the streptozotocin (STZ) diabetic rat, American Journal of Physiology: Heart and Circulatory 294: H1609-H1620, 2008.
Sharma V.* and McNeill, J.H., Diabetic cardiomyopathy: where are we 40 years later?, Canadian Journal of Cardiology, 22: 305-308, 2006.
Sharma V.* and McNeill J.H., The etiology of hypertension in the metabolic syndrome. Part One: An Introduction to the History, the Concept and the Models, Current Vascular Pharmacology 4: 293-305, 2006.
Sharma V.* and McNeill J.H., The etiology of hypertension in the metabolic syndrome: Part Two: The Gene-Environment Interaction, Current Vascular Pharmacology 4: 294-320, 2006.
Sharma V.* and McNeill J.H., The etiology of hypertension in the metabolic syndrome: Part Three: Regulation and Dysregulation of Blood Pressure, Current Vascular Pharmacology 4: 321-348, 2006.
Sharma V.* and McNeill J.H., The etiology of hypertension in the metabolic syndrome: Part Four: The Systemic Perspective: The Role of the Neuroendocrine and Immune Systems and the Challenge of Integration, Current Vascular Pharmacology 4: 349-381, 2006.
Sharma V. and McNeill J.H., The emerging roles of leptin and ghrelin in cardiovascular physiology and pathophysiology, Current Vascular Pharmacology 3:169-80, 2005.
Dr. Vijay Sharma does not hold a share or financial interest in the Rutherford Cancer Centres or another Rutherford Health plc company.
Dr. Vijay Sharma does not have a share or financial interest in equipment used at the Rutherford Cancer Centres or another Rutherford Health plc company.
Dr. Vijay Sharma does not hold any paid advisory role(s) at the Rutherford Cancer Centres or on behalf of Rutherford Cancer Centres or Rutherford Health plc.
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