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08 / 03 / 21

Treating head and neck cancer with proton therapy


Overview

Proton particles do not deposit an exit dose, which allows proton therapy to spare normal tissues distal to the tumour target. This is particularly useful for treating head and neck tumours because of the anatomic constraints encountered in nearly all cancers in this region.

Proton therapy enables the delivery of aggressive local therapy. Proton therapy for paranasal sinus tumours reported improved local control and survival.9,10 A recent meta-analysis also reported that proton therapy was superior to IMRT in both disease-free survival (72% vs. 50% at 5 years) and tumour control (81% vs. 64%).

The dosimetric advantage unique to proton therapy translates into toxicity reduction. Studies comparing proton versus photon therapy have reported significantly lower rates of acute > grade 2 dysphagia, dysgeusia, mucositis and nausea favouring proton therapy. Additionally, proton therapy resulted in the prevention of weight loss, lower opioid use, and less gastrostomy tube dependence.

IBA White Paper

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Consultants we currently work with (head & neck)

Dr Josef Kovarik

Dr Josef Kovarik is an acting consultant clinical oncologist and a Lead of ENT Oncology at the Northern Centre for Cancer...

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Dr Josef Kovarik

Dr Shanmugasundaram Ramkumar

Dr Ramkumar is a Consultant Clinical Oncologist specialising in non-surgical treatment of Head and Neck cancer, Skull Base Tumours and...

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Dr Shanmugasundaram Ramkumar

Dr Eleanor Aynsley

Dr Aynsley graduated from Leeds Medical School in 1999. She did medical training in Durham, gaining MRCP in 2004. She...

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Dr Eleanor Aynsley

Dr Muthiah Sivaramalingam

Dr Muthiah Sivaramalingam has been a consultant in Clinical Oncology since 2007 and has been Principal Investigator for many clinical...

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Dr Muthiah Sivaramalingam

Dr Cheng Boon

Dr Cheng Boon is Consultant Clinical Oncologist at the Worcester Oncology Centre at Worcester Royal Hospital. He completed medical training...

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Dr Cheng Boon

Dr Russell Banner

Dr Russell Banner is a Consultant Clinical Oncologist based in South Wales. His undergraduate training was at Christ’s College, Cambridge...

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Dr Russell Banner

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