Proton beam therapy is an advanced form of external radiotherapy that uses high-energy proton beams instead of photon x-ray beams or electrons. Carefully measured doses of protons are delivered to the precise area needing treatment, using the latest IBA ProteusONE technology. This ensures that the delivery of proton beam therapy is highly accurate and prevents the risk of radiation reaching surrounding healthy tissue.
Radiotherapy is used to kill and destroy cancer cells. It utilises radiation in the form of high-energy x-rays, known as photons, to kill and damage the cancerous cells and prevent their growth and reproduction. It can be used as a non-surgical option to treat cancer, and it can also be used to shrink a tumour or in combination with other treatments.
The Rutherford Cancer Centres and Elekta are bringing the next generation of personalised adaptive radiotherapy technology to oncology centres across the UK, with the new MR-linac Elekta Unity now available at the Rutherford Cancer Centre North West in Liverpool.
Worldwide, lung cancer is the most common cancer among men in both incidence and mortality, and among women has the third-highest incidence and the second in mortality. In the United States, lung cancer remains the number one cause of cancer mortality both in men and women. Lung cancer is categorized as small cell lung cancer and non-small cell lung cancer (NSCLC), with close to 80% of patients presenting with NSCLC. Approximately 15-20% of NSCLC are surgically resectable, and about 75% of patients present with locally advanced or metastatic disease at the time of diagnosis. For patients with locally advanced disease, and some patients with early-stage disease that are unable to tolerate surgery, the current standard therapy is radiation therapy +/- chemotherapy. Other cancers of the thorax, such as thymoma and mesothelioma, are also routinely treated with radiation therapy in some scenarios.
Proton therapy has been used in treating lung cancer for decades. There is a substantial body of evidence as to the efficacy of proton therapy in radiation treatment for lung cancer. With the latest delivery technique, pencil beam scanning (PBS), equipped with motion mitigation and plan optimization, intensity-modulated proton therapy (IMPT) achieves better conformality and greater sparing of critical structures than photon radiation.
This whitepaper aims to provide existing clinical data when considering treatment options that benefit patients the most.
IBA White Paper
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